Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.
Position Summary
We are seeking a highly accomplished Staff Software Engineer to lead the design and delivery of scalable, cloud-native platforms across enterprise and integration ecosystems. This role requires deep expertise in AWS cloud architecture, Java/Python development, and enterprise integration patterns, along with a focus on AI/ML-driven solutions.
Key Responsibilities
- Design and develop scalable systems using Java and/or Python
- Architect cloud-native solutions on AWS
- Build enterprise integration frameworks using APIs and event-driven patterns
- Develop microservices and distributed systems
- Integrate enterprise platforms like Salesforce and third-party systems
- Develop AI-powered solutions for automation and insights
- Ensure system scalability, security, and performance
- Drive CI/CD and engineering best practices
- Mentor engineers and provide leadership
Required Qualifications
- 8+ years of experience in software engineering with strong expertise in Java and/or Python
- Proven experience designing and scaling cloud-native applications on AWS
- Deep understanding of distributed systems, microservices, and API-driven architectures
- Strong experience in enterprise integration patterns, including asynchronous and event-driven systems
- Demonstrated ability to design modular, reusable platforms and components
- Experience integrating with enterprise systems such as Salesforce or similar platforms
- Strong knowledge of security, compliance, and access control frameworks
- Excellent communication skills with the ability to influence technical and non-technical stakeholders
Preferred Qualifications
- Experience with healthcare systems (HL7/FHIR)
- Experience with Salesforce integrations
- Exposure to AI/ML and LLM-based applications
- Experience with observability tools and DevOps practices
Success Metrics
- Deliver scalable AWS architectures
- Build reusable platforms to accelerate development
- Reduce system complexity and technical debt
- Improve system reliability and performance
- Drive AI-driven automation and insights
Within the range, individual pay is determined by work location and additional factors, including, but not limited to, job-related skills, experience, and relevant education or training. If you are selected to move forward, the recruiting team will provide details specific to the factors above.
Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to [Confidential Information]
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.
Please visit our career page at: http://www.guardanthealth.com/jobs/ 
