Senior Infrastructure Engineer

Guardant Health is a pioneer in non-invasive cancer diagnostics and the first company to commercialize a comprehensive genomic liquid biopsy. Our proprietary digital sequencing technology is transforming cancer treatment by providing an accurate and precise picture of the individual genomic alterations that cause tumors to grow, change, and develop resistance to treatment. We have combined decades of scientific research, advances in laboratory technology, and our breakthrough innovation in liquid biopsy to create new tests that have already handled tens of thousands of samples. We believe our tests can accelerate new drug development and improve the lives of all patients fighting cancer. Our current products are just the beginning of what we hope to accomplish, and new uses of our platform are emerging.

We succeed best by coordinating our creative talents and energies, working as a team to achieve results far beyond what any single individual could accomplish. We seek very talented people who want to be part of our fantastic team.

Job Description

Guardant's HPC team builds and operates the computational technology backbone of the company.

This includes scalable data storage that holds PBs of genomics data, high performance compute clusters running a custom bioinformatics pipeline in production and R&D environments, and the software infrastructure that hosts an ecosystem of services for internal data processing and external data integration. To facilitate Guardant Health's fast growth in the next few years, the HPC team is looking for a strong technical engineer who can help maintain and help grow the HPC infrastructure during its aggressive expansion, while working with corporate IT, SQA and DevOps/SRE teams.

This role can be remotely worked part-time, but requires a very hands on, on-premise presence when on rotation, minimally.

In this role, you will primarily:

• Help manage multiple HPC clusters and cluster file systems.
• Help research, develop and implement the next generation HPC solution
• Troubleshoot the production system stack down to source code level e.g. shell scripts, python and others.
• Maintains, monitors, and supports the infrastructure environment and/or facilities.
• Used and maintained enhanced production monitoring and additional capability.
• Support improvements for increased system reliability and performance.
• Supports in a senior role multiple systems or applications of medium to high complex (complexity defined by size, technology used, and system feeds and interfaces) with multiple concurrent users, ensuring control, integrity, and accessibility.
• Work with offsite consultants to maintain the infrastructure
• Work with vendors to troubleshoot, upgrade and repair systems as needed
• Participate in a 24/7 on-call rotation

About You:

You enjoy an agile, very fast paced and highly technical environment. You are a self-driven accomplished technologist who strives to be ever improving your skills, value to the company and improve the computational infrastructure. You are dedicated to engineering excellence yet pragmatic and flexible. You have the ability to maintain the day-to-day support SLA while running various key projects that move the business forward.

• 4+ years of Linux/Unix administration, knowledge of Unix network protocols, TCP/IP network fundamentals, core infrastructure technologies and virtualization
• 4+ years of large-scale data storage and compute clusters (HPC) infrastructure
• 2+ years working in and with on-premise and cloud-based (AWS, Google, IBM and Azure) data-centres
• 3+ years of building software release and ops processes and automation toolset
• 4+ years providing documentation of system administration

Following Skills Sets are Preferred:

• Experience administering IBM's General Parallel File System

• Experience administering SLURM scheduler
• Experience with cloud bursting technologies
• Experience with wide area file systems
• Experience with docker and container technologies
• Experience with Kubernetes, preferably with Certified Kubernetes Administrator (CKA)
• Operating infrastructure compliant with HIPAA and SOX standards

Education

B.S. in Computer Science or related field