Principal Scientist, Global Proteomics

This job is with Johnson & Johnson, an inclusive employer and a member of myGwork the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Discovery & Pre-Clinical/Clinical Development

Job Sub Function

Biological Research

Job Category

Scientific/Technology

All Job Posting Locations:

Cambridge, Massachusetts, United States of America

Job Description

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Principal Scientist, Global Proteomics to be located in Cambridge, MA.

Purpose: Do you want to use your hardearned skills and drive to make a difference in the lives of patients Join the growing Discovery Proteomic Platforms (DPP) group within the Discovery Technologies and Molecular Pharmacology (DTMP) department of Therapeutics Discovery to apply groundbreaking approaches to highscale proteomic analysis! Be part of a motivated team deploying innovative mass spectrometry technologies to tackle challenges in endtoend drug discovery and development across a leading multiomics organization. We work shouldertoshoulder across biology, chemistry, and data science to deliver clear, reproducible proteomic readouts that move medicines forward. With your help, we will drive development of medicines for our patients!

In this role, you will lead global target deconvolution proteomics efforts at scale. You'll build robust, automated workflows and partner with experts across the organization to translate clear, reproducible data into meaningful insights that propel programs forward.

You Will Be Responsible For

• Translating scientific goals into highthroughput, automationready proteomics workflows with QC and fitforpurpose SOPs that enable consistency across studies and operators.
• Serving as the proteomics point of contact for assigned programs; aligning on study strategy, timelines, and readouts; communicating results clearly to biology, chemistry, biologics, safety, DMPK, and clinical translation partners.
• Partnering with bioinformatics and IT to ensure FAIR data practices, robust QC pipelines, and timely, decisionready analyses; harmonizing effort with multiomics colleagues for coordinated readouts.
• Mentoring and uplifting teammates-sharing massspec standard processes, reviewing methods and data, and contributing to a culture of scientific excellence, safety, and continuous improvement.
  
  

Qualifications / RequirementsEducation

• A Doctorate degree in Analytical Chemistry, Biochemistry, Chemical Biology, Molecular Biology, Pharmacology or a related field is required.
  
  

Experience and Skills:Required:

• 6+ years of handson proteomics mass spectrometry experience, including 3+ years in a drug discovery setting (pharma, biotech, or equivalent applied environment) is required.
• Demonstrated leadership in unbiased, probefree target deconvolution (e.g., CETSA/TPP, LIPMS, SPROX, PISA, limitedproteolysis/structural proteomics), from study design through interpretation is required.
• Proven track record industrializing methods: automationsupported sample prep, robust QC, SOPs, and multioperator reproducibility is required.
• Strong communication and crossfunctional collaboration skills; effective planning and the ability to run several projects in a fastpaced environment is required.
• Technical toolkit - Experience with at least one tool from each area is required:
• LCMS & LC systems: Thermo Orbitrap Exploris/Eclipse/Fusion Lumos/Astral; Bruker timsTOF; Vanquish Neo, Evosep One, Dionex UltiMate.
• Automation Platforms: Hamilton Microlab STAR, Tecan Fluent, AssayMAP Bravo, Beckman Biomek, Dynamic Devices Lynx.
• Data analysis (labelfree included): Proteome Discoverer, MaxQuant, DIANN, Spectronaut, Skyline.
  

Preferred

• Experience scaling platformlevel methods and implementing automationready protocols is preferred.
• Expertise in PTMfocused proteomics and/or exposure to singlecell or spatial proteomics workflows is preferred.
• Record of scientific innovation (publications, patents) and external visibility (e.g., ASMS, HUPO) is preferred.
• Familiarity with fitforpurpose quality systems, LIMS, and FAIR data principles is preferred.
  
  

The anticipated base pay range for this position is $117,000 to $201,250.

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis.

• Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
• Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).
• Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits:
  
  

6258516 Director, Software / Systems Engineering ![CDATA[ p strong em This job is with Johnson Johnson, an inclusive employer and a member of myGwork the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly. /em /strong /p pAt Johnson amp; Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at spanjnj.com/span./ppAs guided by Our Credo, Johnson amp; Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson amp; Johnson, we respect the diversity and dignity of our employees and recognize their merit./ppstrongspanspanJob Function: /span/span/strong/pTechnology Product amp; Platform Managementp/pp/ppstrongspanspanJob Sub /span/spanspanspanFunction: /span/span/strong/pMulti-Family Technology Product amp; Platform Managementp/pp/ppstrongJob Category:/strong/pProfessionalp/pp/ppstrongAll Job Posting Locations:/strong/pBangalore, Karnataka, Indiap/pp/ppstrongJob Description:/strong/ppspanstrongJob Description Summary/strong/span/ppspan /span/ppspanDirects Managers and/or senior individual contributors in a matrix environment, and is accountable for meaningful career development conversations and regular coaching and feedback. /span/ppspanAdministers the Digital Surgery Platform Software / Systems Engineering plan and develops processes and procedures that support business goals. /span/ppspanMonitors initiatives and oversees timelines, approvals, and communication plans. Contributes to planning of strategic initiatives and serves as a primary point of contact for internal and external stakeholders./span/ppspan /span/ppspanstrongJob Description/strong/span/ppspan /span/ppspanKey responsibilities will include, but not limiting to:br /

• Lead and drive the team responsible for design and development of device connectivity software and its adoption into the eco-system of Connected MedTech Devices. br /
• Continually drive improvement and adoption of best-in-class engineering practices across the agile teams of the Digital Surgery Platform. br /
• Be responsible for delivering advanced solutions that directly impact Patients and Physicians outcomes by leveraging advances in MedTech and Medical Devices. br /
• Bring strong thought leadership around IoT Device Lifecycle Management, IOT security, Device Applications Lifecycle Management, Cloud Platform Technologies, and production grade Quality.br /
• Will lead the adoption of modern engineering practices and the continuous improvement in quality across the digital surgery program.br /
• Collaborate and influence other engineers and org leaders and drive execution to success. br /
• Deliver to the strategy and roadmap items of MedTech Device Engineering deliverables through the design, development, and deployment phases for all MedTech devices in Digital Surgery Platform (DSP) portfoliobr /
• Engage in the architecture and design of the platform, as a key member of the DSP architecture team. br /
• Leverage CI/CD practices to plan and manage resources for both internal and development partners. Maintain a standard engineering toolset, leveraging Jamp;J enterprise standards where applicable and leading the adoption of new-to-Jamp;J technologies where appropriate. Lead DevSecOps technology decisions. Guide the teams in making appropriate product development choices and ensure the toolset and pipeline framework supports the selected choices (development language, IDE, testing and validation framework, and other toolsets).br /
• Implement a shift-left strategy, applying tools and techniques such as code scanning to improve security and identify issues earlier in the lifecycle. br /
• Negotiate, organize, and prioritize deliverables based on impact, need and ROI; clearly communicate to development teams, the product features, timeline and KPI needed to meet performance goals.br /
• Act as a coach and servant leader to the distributed DSP device team, and the engineering organization. br /
• Mentor junior members of the engineering staff to expand design team abilities and establish good working practices br /
• Ensure the engineering pipelines support the traceability and other requirements of the Quality Management System, in an efficient manner and without compromising the broader quality approach (e.g. through inappropriate use of UI-based testing). Automate and integrate with other systems (Jira/X-Ray for test evidence and ServiceNow) where this will improve efficiency or reduce manual error. br /
• Thought Leader for the broader JJT engineering and device engineering community and Ensure the Digital Surgery program learns from and gives back to the broader community. br /
• Advisor and SME to the broader MedTech Ramp;D/IT engineering strategy, for example on the tradeoffs between standardization/reuse and decoupling/independence, from an engineering practitioner's perspective. br /
• Research and stay ahead of emerging technology, industry, and regulatory trends to build a competitive advantage./span/ppspan /span/ppspanRequisition for a pre-identified internal candidate's movement/span/pp/pp/pp /pp /ppstrongRequired Skills: /strong/pp /pp /ppstrongPreferred Skills:/strong/pBusiness Architecture, Business Process Design, Business Savvy, Computer Programming, Emerging Technologies, Human-Computer Interaction (HCI), Leadership, Organizational Change Management, Platform as a Service (PaaS), Product Knowledge, Program Management, Software Development Management, Strategic Change, Tactical Planning, Technical Credibility]] Hospital Health Care Full-time Bangalore, Karnataka India IN https://mygwork.com/jobs/johnson-johnson-director-software-systems-engineeringsrc=linkedinutm_source=linkedinutm_medium=referralutm_campaign=jobs Johnson Johnson ![CDATA[ p strong em This job is with Johnson Johnson, an inclusive employer and a member of myGwork the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly. /em /strong /p pAt Johnson amp; Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at spanjnj.com/span./ppAs guided by Our Credo, Johnson amp; Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson amp; Johnson, we respect the diversity and dignity of our employees and recognize their merit./ppstrongspanspanJob Function: /span/span/strong/pTechnology Product amp; Platform Managementp/pp/ppstrongspanspanJob Sub /span/spanspanspanFunction: /span/span/strong/pMulti-Family Technology Product amp; Platform Managementp/pp/ppstrongJob Category:/strong/pProfessionalp/pp/ppstrongAll Job Posting Locations:/strong/pBangalore, Karnataka, Indiap/pp/ppstrongJob Description:/strong/ppspanstrongJob Description Summary/strong/span/ppspan /span/ppspanDirects Managers and/or senior individual contributors in a matrix environment, and is accountable for meaningful career development conversations and regular coaching and feedback. /span/ppspanAdministers the Digital Surgery Platform Software / Systems Engineering plan and develops processes and procedures that support business goals. /span/ppspanMonitors initiatives and oversees timelines, approvals, and communication plans. Contributes to planning of strategic initiatives and serves as a primary point of contact for internal and external stakeholders./span/ppspan /span/ppspanstrongJob Description/strong/span/ppspan /span/ppspanKey responsibilities will include, but not limiting to:br /
• Lead and drive the team responsible for design and development of device connectivity software and its adoption into the eco-system of Connected MedTech Devices. br /
• Continually drive improvement and adoption of best-in-class engineering practices across the agile teams of the Digital Surgery Platform. br /
• Be responsible for delivering advanced solutions that directly impact Patients and Physicians outcomes by leveraging advances in MedTech and Medical Devices. br /
• Bring strong thought leadership around IoT Device Lifecycle Management, IOT security, Device Applications Lifecycle Management, Cloud Platform Technologies, and production grade Quality.br /
• Will lead the adoption of modern engineering practices and the continuous improvement in quality across the digital surgery program.br /
• Collaborate and influence other engineers and org leaders and drive execution to success. br /
• Deliver to the strategy and roadmap items of MedTech Device Engineering deliverables through the design, development, and deployment phases for all MedTech devices in Digital Surgery Platform (DSP) portfoliobr /
• Engage in the architecture and design of the platform, as a key member of the DSP architecture team. br /
• Leverage CI/CD practices to plan and manage resources for both internal and development partners. Maintain a standard engineering toolset, leveraging Jamp;J enterprise standards where applicable and leading the adoption of new-to-Jamp;J technologies where appropriate. Lead DevSecOps technology decisions. Guide the teams in making appropriate product development choices and ensure the toolset and pipeline framework supports the selected choices (development language, IDE, testing and validation framework, and other toolsets).br /
• Implement a shift-left strategy, applying tools and techniques such as code scanning to improve security and identify issues earlier in the lifecycle. br /
• Negotiate, organize, and prioritize deliverables based on impact, need and ROI; clearly communicate to development teams, the product features, timeline and KPI needed to meet performance goals.br /
• Act as a coach and servant leader to the distributed DSP device team, and the engineering organization. br /
• Mentor junior members of the engineering staff to expand design team abilities and establish good working practices br /
• Ensure the engineering pipelines support the traceability and other requirements of the Quality Management System, in an efficient manner and without compromising the broader quality approach (e.g. through inappropriate use of UI-based testing). Automate and integrate with other systems (Jira/X-Ray for test evidence and ServiceNow) where this will improve efficiency or reduce manual error. br /
• Thought Leader for the broader JJT engineering and device engineering community and Ensure the Digital Surgery program learns from and gives back to the broader community. br /
• Advisor and SME to the broader MedTech Ramp;D/IT engineering strategy, for example on the tradeoffs between standardization/reuse and decoupling/independence, from an engineering practitioner's perspective. br /
• Research and stay ahead of emerging technology, industry, and regulatory trends to build a competitive advantage./span/ppspan /span/ppspanRequisition for a pre-identified internal candidate's movement/span/pp/pp/pp /pp /ppstrongRequired Skills: /strong/pp /pp /ppstrongPreferred Skills:/strong/pBusiness Architecture, Business Process Design, Business Savvy, Computer Programming, Emerging Technologies, Human-Computer Interaction (HCI), Leadership, Organizational Change Management, Platform as a Service (PaaS), Product Knowledge, Program Management, Software Development Management, Strategic Change, Tactical Planning, Technical Credibility]]