Pathology Technician

The Technician Histopathology and Clinical Pathology will be responsible for assisting in the preparation, processing, and analysis of biological and tissue samples as part of GLP-compliant preclinical studies. The role supports study pathologists and clinical pathology staff in performing necropsy, histopathology, and clinical pathology procedures to ensure accurate data collection, integrity, and timely reporting.

Acquire and maintain knowledge of the Principles of Good Laboratory Practice (GLP) relevant to pathology operations.

Assist Study Director / Study Pathologist in the conduct of studies as per GLP compliance.

Follow the approved Study Plan and applicable Standard Operating Procedures (SOPs).

Ensure adherence to instructions and procedures mentioned in the study plan, SOPs, and training records.

Assist in animal euthanasia, dissection, and organ/tissue collection under supervision.

Record organ weights, perform trimming of tissues, and prepare specimens for fixation as per SOPs.

Perform tissue processing, embedding, microtomy (sectioning), staining (H&E and special stains), and slide mounting with accuracy.

Maintain labeling integrity, cleanliness, and sample traceability throughout processing.

Support Study Pathologist during microscopic evaluation and slide organization.

Collect blood, urine, and other biological fluids from animals as per study requirements and aseptic procedures.

Prepare serum/plasma and maintain biological samples under appropriate storage conditions.

Perform smears for Differential Leukocyte Count (DLC), Reticulocyte Count, and bone marrow examination.

Carry out staining procedures and accurately record results under supervision.

Ensure sample handling and testing adhere to the defined timeframes and GLP documentation practices.

Operate and maintain laboratory instruments such as microtomes, tissue processors, centrifuges, hematology analyzers, and microscopes.

Participate in equipment qualification (IQ/OQ/PQ), calibration, and preventive maintenance as per SOPs.

Record usage, calibration, and maintenance data in logbooks accurately.

Report instrument malfunctions or deviations immediately to the responsible person or supervisor.

Record all raw data legibly, promptly, and accurately in bound notebooks or approved electronic formats following ALCOA+ principles.

Ensure that entries are signed, dated, and traceable.

Report deviations or observations immediately to the Study Pathologist or Quality Assurance Unit (QAU).

Ensure that tissue blocks, slides, and data are properly archived after study completion.

Support method standardization or validation activities for new staining techniques, analytical methods, or clinical assays.

Participate in reproducibility or verification studies under supervision.

Follow established validation protocols and document all steps appropriately.

Manage receipt, labeling, preparation, and storage of reagents, stains, and consumables.

Maintain stock inventory, ensure timely procurement, and check expiry dates.

Handle and dispose of chemical and biological waste as per EHS and biosafety guidelines.

Coordinate with QAU, Study Director, and other departments for sample collection, processing, and reporting.

Participate in internal audits and inspections by providing required records or clarifications.

Follow CAPA (Corrective and Preventive Action) instructions when applicable.

Attend in-house and external training sessions as instructed by management.

Maintain training records and competency evaluations for each technical activity performed.

Assist in training junior technicians or new staff under supervision.

Follow all Environment, Health, and Safety (EHS) procedures during necropsy, tissue handling, and laboratory activities.

Always wear prescribed personal protective equipment (PPE).

Report injuries, unsafe conditions, or accidents to the supervisor immediately.

Maintain cleanliness and orderliness in the laboratory work area.

Archive all instrument records, logbooks, and calibration certificates as per retention schedule.

Label and store slides, blocks, and samples in designated archival areas under controlled conditions.

Ensure traceability and retrievability of all archived materials.

Review and provide inputs for SOPs relevant to laboratory activities.

Assist in preparing or revising departmental SOPs under supervision of Study Pathologist or TFM.

Participate in planning, execution, and data documentation of pathology-related study activities.

Support Test Facility Management (TFM) in maintaining GLP compliance and operational readiness.

Perform any other tasks assigned by the Study Pathologist or TFM as per study or departmental needs.

Strong attention to detail and accuracy in laboratory techniques.

Good understanding of sample handling, tissue processing, and staining procedures.

Familiarity with clinical pathology workflows and data recording formats.

Ability to follow SOPs and GLP documentation principles.

Effective communication and teamwork skills.

B.Sc. / M.Sc. in Life Sciences, Biotechnology, Zoology, or equivalent discipline.

DMLT or related certification preferred.

310 years of experience in histopathology or clinical pathology within a GLP / biomedical research or diagnostic setup.

Experience with rodent necropsy, tissue trimming, microtomy, staining, and clinical sample handling preferred.

Exposure to GLP documentation and quality systems desirable.

Timely and accurate completion of laboratory tasks.

Compliance with GLP documentation and SOPs.

Quality of tissue preparation and slide presentation.

Readiness during audits and inspections.

• Team collaboration and responsiveness to study requirements.