Consultant Biostatistician (SLR, Meta-analysis & NMA)

Engagement Type

• Independent Consultant / Contract Position
• Initial Engagement: 6 Months
• Project-specific assignment with possibility of extension not full time engagement
• Rate card-based engagement for future projects subject to business requirements and consultant availability
• Remote / Hybrid (as applicable)

We are seeking an experienced Biostatistics Consultant with deep expertise in Systematic Literature Reviews (SLR), Meta-analysis, Indirect Treatment Comparisons (ITC), and Network Meta-analysis (NMA) to support ongoing HEOR, Market Access, and Evidence Synthesis projects.

The consultant will work directly with client-facing project teams and will be expected to independently lead statistical components of evidence generation projects for global pharmaceutical and biotech clients. The role requires proven experience in delivering high-quality analyses, interpreting complex evidence, and presenting findings to client stakeholders.

Scope of Work:

1. Evidence Synthesis

• Lead and execute Systematic Literature Reviews (SLRs) in accordance with PRISMA, Cochrane, NICE, and HTA standards.
• Develop review protocols, study eligibility criteria, and data extraction frameworks.
• Support literature screening, study selection, and evidence synthesis activities.
• Critically appraise clinical evidence and assess study quality.

2. Advanced Statistical Analysis

• Conduct pairwise and direct meta-analyses.
• Perform Bayesian and/or Frequentist Network Meta-Analyses (NMA).
• Conduct Indirect Treatment Comparisons (ITC) and Mixed Treatment Comparisons (MTC).
• Perform sensitivity analyses, subgroup analyses, heterogeneity assessments, and meta-regression.
• Develop forest plots, network diagrams, league tables, and treatment rankings.

3. HEOR and HTA Support

• Support evidence packages for HTA and reimbursement submissions.
• Generate methodology documentation, statistical reports, and publication-ready outputs.
• Collaborate with health economists, epidemiologists, medical writers, and market access teams.

4. Client Engagement

• Participate in client discussions and methodology workshops.
• Translate business questions into suitable analytical methodologies.
• Present findings and recommendations to internal and external stakeholders.
• Provide scientific and statistical input during project planning and proposal discussions.

Mandatory Experience

• Advanced degree in Biostatistics, Statistics, Epidemiology, Public Health, Pharmacy, Mathematics, or related discipline.
• Minimum 8+ years of relevant experience in: Systematic Literature Reviews (SLR), Meta-analysis (direct), Network Meta-analysis (NMA; Bayesian and/or Frequentist), and Indirect Treatment Comparisons (ITC)
• Proven experience supporting pharmaceutical, biotech, CRO, or consulting clients.
• Demonstrated experience delivering multiple end-to-end evidence synthesis projects independently.
• Prior experience supporting HTA submissions is highly desirable.
• Should be able to work in R software for running the analysis
• Should have knowledge and experience on methods: Mixed Treatment Comparisons, Meta-regression, Survival Analysis, Fixed and Random Effects Models and Evidence Grading Frameworks (GRADE preferred)
• Therapeutic area exposure across Oncology, Neurology, Immunology, Rare Diseases, or Cardiometabolic conditions.