Job Description
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Chemist (often at Bristol Myers Squibb) develops, optimizes, and scales up chemical processes for drug manufacturing, involving synthetic/analytical chemistry, process development, data analysis, and troubleshooting complex reactions for new therapies (small molecules, peptides, etc.), requiring strong organic chemistry skills, analytical techniques (NMR, MS, Chromatography), and collaboration with engineering/manufacturing teams to ensure safe, economical, and quality production from lab to clinical scale.
Key Responsibilities (Examples from BMS):
Process Development: Design and improve synthetic routes for drug candidates.
Scale-Up: Develop knowledge for transitioning processes from lab to clinical manufacturing.
Analysis & Characterization: Use techniques like chromatography, NMR, Mass Spec (MS), IR spectroscopy to purify and identify compounds.
Data Management: Analyze, compile, and share experimental data with project teams.
Collaboration: Work closely with analytical chemists and engineers.
Problem Solving: Troubleshoot complex chemical and manufacturing issues.
Documentation: Support regulatory filings with process knowledge.
Typical Qualifications:
Education: PhD or MSc in Organic Chemistry or related field.
Experience: Strong background in synthetic organic chemistry, reaction mechanisms, purification, and characterization.
Skills: Excellent problem-solving, data analysis, technical writing, and communication skills.
Specific Experience (May vary): Radiochemistry, gloveboxes, ICP-MS, electrochemistry, etc., for specialized roles.
In essence, a BMS Chemist bridges the gap between early-stage drug discovery and large-scale medicine production, ensuring efficient, safe, and high-quality chemical processes.