Scientist I, Protein Biology

Job Description :

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Cold Room/Freezers -22degreesF/-6degrees C, Laboratory Setting, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

About Company:

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of approximately $44 billion. Whether our customers are accelerating life sciences research, solving analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies, purchasing convenience, and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD.

About Team: Antibody team

The antibody team is involved in engineering and development of recombinant antibodies, with a strong focus on reagent quality and specificity. The core activities of team include antibody designing, purification, conjugation and testing of antibodies in a variety of immuno-applications using groundbreaking tools and technologies. The goal of the program is product development and creation of product specific information to promote research use.

Role & Responsibilities

Role:

Scientist in an antibody development team with a focus on performance and specificity using innovative molecular biology methods and immunoassays.

Responsibilities:

• Meticulous experimental planning and execution to meet program goals.
• Excellent record keeping of results in data sheets and laboratory notebooks.
• Regular mining of literature and keeping oneself up to date with developments in field of antibody development.
• Compilation and presentation of data in written and oral formats. Active participation in team meetings.
• Attention to detail and adherence to schedules.

Candidate Requirement:

Education & Experience levels:

Applicants should have Master with 0-3 years confirmed experience or a fresh PhD (within one year of completion) in a life sciences field related to molecular biology, immunology, biotechnology or biochemistry.

Nature of experience:

• Demonstrated experience in immunoassays such as Western blotting, Immunofluorescence, Immunohistochemistry, Flow cytometry and ELISA.
• Theoretical or practical experience in antibody development platforms is desirable.
• Experience and knowledge in protein purification and analysis technologies such as affinity or ion exchange chromatography, SEC, HPLC, and SDS-PAGE. Experience with protein affinity measurements and epitope binning is desirable
• Experience with proteins, which could include but not limited to structure function or mutational analysis of proteins, and molecular biology expertise in handling nucleic acid extraction, PCR, cloning, antibody or protein engineering and rational design of mutants. Experience or familiarity with antibody or protein engineering, rational design of mutants, and molecular biology. Experience with structural biology and protein modeling and visualization tools such as Pymol, Shrodinger, Discovery Studio or other such programs is desirable.
• Familiarity or experience in development of conjugation chemistry or performing antibody conjugation.
• Project or work experience in support of relevant skills such as publications, project reports or thesis work.
• Proficient in MS Office applications such as Word, Power point, Excel and possess a strong statistical knowledge and familiarity with statistical software such as Prism.

The successful candidate will be self-motivated and a self-starter who is excellent at learning and applying new concepts for process or product improvements, possesses excellent oral and written communication skills to connect to peers and leadership, and will be an excellent teammate with the ability to work with diverse colleagues.

Thermo Fisher Scientific is an equal opportunity employer and value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics, pregnancy, disability or any other legally protected status. Thermo Fisher Scientific aligns with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer a company culture that stands for integrity, intensity, involvement, and innovation!